Publications and preprints

(a). Research Papers (with links to PDF or open-access full text)

Wang X, Jiang W, Luo S, Yang X, Wang C, Wang B, Dang Y, Shen Y, Ma, D.K.* The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex. bioRxiv doi: 

Zhang Z, Luo S, Barbosa GO, Bai M, Kornberg TB, Ma, D.K.* The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response. PLoS Genetics (2021) e1009317. doi: 10.1371/journal.pgen.1009317.

Luo S, Wang X, Bai M, Jiang W, Zhang Z, Chen Y, Ma, D.K.* The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics. Proceedings of the National Academy of Sciences (2021) Feb 9;118(6):e2011379118. doi: 10.1073/pnas.2011379118.

Singhal, N., Bai, M., Lee, E. M., Luo, S., Cook, K.R., Ma, D.K.* Cytoprotection by a naturally occurring variant of ATP5G1 in Arctic ground squirrels. eLife (2020) ;9:e55578 DOI: 10.7554/eLife.55578.

Zhang, Z., Bai, M., Barbosa, G., Chen A., Wei, Y., Luo, S., Wang, X., Wang, B., Tsukui, T., Li, H., Sheppard D., Kornberg, T.B., Ma, D.K.* Broadly Conserved Roles of TMEM-131 Family Proteins in Intracellular Collagen Assembly and Secretory Cargo Trafficking. Science Advances (2020) Vol. 6, no. 7, eaay7667 DOI: 10.1126/sciadv.aay7667.

Lee, D., An, S., Jung, Y., Yamaoko, Y., Ryu, Y., Go, G., Beigi, A., Yang., J.S., Jung G.Y., Ma, D.K., Ha, C., Taubert, S., Lee, Y., Lee, S.J. MDT-15/MED15 permits longevity at low temperature via enhancing lipidostasis and proteostasis. Plos Biology (2019) 17(8):e3000415 doi: 10.1371/journal.pbio.3000415.

Chen S, Luo S, Zhang Z, Ma D.K.* VHL-1 inactivation and mitochondrial antioxidants rescue C. elegans dopaminergic neurodegeneration. Protein Cell. (2019) 10(8):610-614. PMID: 30945137. doi: 10.1007/s13238-019-0621-4.

Xu Z, Hu Y, Deng Y, Chen Y, Hua H, Huang S, Nie Q, Pan Q, Ma, D.K., Ma L. WDR-23 and SKN-1/Nrf2 Coordinate with the BLI-3 Dual Oxidase in Response to Iodide-Triggered Oxidative Stress. G3 (Bethesda) (2018) pii: g3.200586.2018. doi: 10.1534/g3.118.200586.

Vozdek. R., Long. Y., Ma, D.K.* The receptor tyrosine kinase HIR-1 Coordinates HIF-independent Response to Hypoxia-Induced Extracellular Matrix Remodeling. Science Signaling. (2018) Oct. 2 2;11(550). [PDF]

Jiang, W., Wei, Y., Long, Y., Owen, A., Wang, B., Wu, X., Luo, S., Dang, Y., Ma, D.K.* A Genetic Program Mediates Cold-warming Response and Promotes Stress-induced Phenoptosis in C. elegans. eLife. (2018) Apr 17;7. pii: e35037. doi: 10.7554/eLife.35037. [PDF]

Bai, M.R., Vozdek, R., Hnizda, A., Jiang, C., Wang, B., Kuchar, L., Li, T., Zhang, Y., Wood, C., Feng, L., Dang, Y., Ma, D.K.* Conserved Roles of C. elegans and Human MANFs in Sulfatide Binding and Cytoprotection. Nature Communications. (2018) Mar 1;9(1):897. doi: 10.1038/s41467-018-03355-0. [PDF]

Prolyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin. Jiang W, Zhou X, Li Z, Liu K, Wang W, Tan R, Cong X, Shan J, Zhan Y, Cui Z, Jiang L, Li Q, Shen S, Bai M, Cheng Y, Li B, Tan M, Ma D.K., Liu JO, Dang Y. Blood. (2018) 131(12):1325-1336. doi: 10.1182/blood-2017-07-794875. [PDF]

Ma, D.K.*, Li, Z., Lu A., Sun F.,Chen S., Rothe M., Menzel R., Sun F., Horvitz H.R*. Acyl-CoA-dehydrogenase drives heat adaptation by sequestering fatty acids. Cell (2015);161(5):1152-63. *Corresponding authors [PDF]

Keller J., Ellieva A., Ma, D.K., Ju J., Nehk E., Konkel A., Falck J.R., Schunck W.H., Menzel R. CYP-13A12 of the nematode C. elegans is a PUFA-epoxygenase involved in behavioural response to reoxygenation. Biochemical Journal (2014) Nov 15;464(1):61-71. [PDF]

Ma, D.K., Rothe M., Zheng S., Bhatla N., Pender C.L., Menzel R., Horvitz H.R. Cytochrome P450 drives a HIF-regulated behavioral response to reoxygenation by C. elegans. Science (2013) Vol. 341 no. 6145 pp. 554-558. PMID: 23811225 [PDF]

Ma, D.K., Vozdek, R., Bhatla, N., Horvitz, H.R. CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans. Neuron (2012) 73, 925-940. PMID: 22876258 [PDF]

Guo, J.U., Ma, D.K., Mo, H., Ball, M.P., Jang, M.H., Bonaguidi, M.A., Balazer, J.A., Eaves, H.L., Xie, B., Ford, E., Zhang, K., Ming, G.L., Gao, Y., Song, H. Neuronal activity modifies the DNA methylation landscape in the adult brain. Nature Neuroscience (2011) 14(10), 1345-51. PMID: 21874013 [PDF]

Ma, D.K.*, Jang, M.H., Guo, J.U., Flavell, R.A., Ming, G.L., Song, H-j*. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science (2009) 323(5917), 1074-7. PMID: 19119186. *Corresponding authors [PDF]

Ma, D.K., Ponnusamy, K, Song, M.R., Ming, G.L., Song, H-j. Molecular genetic analysis of FGFR1 signalling reveals distinct roles of MAPK and PLCgamma1 activation for self-renewal of adult neural stem cells. Molecular Brain (2009) 2(1), 16. PMID: 19505325 [PDF]

Ma, D.K., Chiang, C.H., Ponnusamy K, Ming, G.L., Song, H-j. G9a and Jhdm2a regulate embryonic stem cell fusion-induced reprogramming of adult neural stem cells. Stem Cells (2008) 26:2131-2141. PMID: 18535151 [PDF]

Duan, X., Chang, J.H., Ge, S., Faulkner, R.L., Kim, J.Y., Kitabatake, Y., Liu, X.B., Yang, C.H., Jordan, J.D., Ma, D.K., Liu, C.Y., Ganesan, S., Cheng, H.J., Ming, G.L., Lu, B, Song, H. DISC1 regulates integration of newly generated neurons in the adult brain. Cell. (2007) 130(6):1146-58. PMID: 17825401 [PDF]

(b). Reviews and commentaries

Singhal NS, Sun CH, Lee EM, Ma, D.K. Resilience to Injury: A New Approach to Neuroprotection? Neurotherapeutics. 2020 Jan 29. PMID: 31997268

Singhal NS, Lee EM, Ma, D.K. Neuronal GDPGP1 and glycogen metabolism: friend or foe? J Cell Biol. 2020 Feb 3;219(2). pii: e202001006. PMID: 31971543

Ma, D.K., Ringstad N. The neurobiology of sensing respiratory gases for the control of animal behavior. Frontiers in Biology. (2012) 7(3):246-253. PMID: 22876258 [PDF]

Ma, D.K., Marchetto M.C., Guo J.U., Ming G.L., Gage F.H., Song H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nature Neuroscience (2010) 13(11):1338-44. PMID: 20975758 [PDF]

Ma, D.K., Kim, W, Ming, G.L., Song, H-j. Activity-dependent extrinsic regulation of adult hippocampal and olfactory bulb neurogenesis. Annals of New York Academy of Sciences (2009) 1170:664-73. PMID: 19686209 [PDF]

Ma, D.K., Bonaguidi, M., Ming, G.L., Song, H-j. Adult neural stem cells in the mammalian central nervous system. Cell Research (2009) 19(6):672-82. PMID: 19436263 [PDF]

Ma, D.K., Guo, J.U., Ming, G.L., Song, H-j. DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation. Cell Cycle (2009) 19(6):672-82. PMID: 19377292 [PDF]

Ma, D.K., Ming, G-l., and Song, H-j. Glial influences on neural stem cell development: cellular niches for adult neurogenesis. Current Opinion in Neurobiology (2005) 15:514-20. PMID: 16144763 [PDF]