Dengke is currently a member of the Cardiovascular Research Institute (CVRI) and Assistant Professor of the Department of Physiology at UCSF School of Medicine. In 2002, Dengke obtained a B.S. degree from the Department of Physics at Tsinghua University in China. From 2002 to 2008, Dengke was a graduate student in the laboratory of Dr. Hongjun Song and received his Ph.D. from the Solomon H. Snyder Department of Neuroscience, at the Johns Hopkins University. His thesis work on molecular regulation of adult mammalian neural stem cells and activity-dependent adult neurogenesis was recognized by the Harold M. Weintraub Graduate Student Award. In 2009, Dengke started as a post-doctoral fellow in the laboratory of H. Robert Horvitz at MIT. In the Horvitz lab, he received training in genetic and neural analyses of animal behavior and identified novel evolutionarily conserved pathways that control how C. elegans responds to tissue hypoxia and reoxygenation. Dengke's postdoctoral work has been supported mainly by the Helen Hey Whitney Foundation postdoctoral fellowship and recognized by the 2013 Peter and Patricia Gruber International Research Award in Neuroscience and the NIH Pathway-to-Independence Award (K99/R00).